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病原生物学研究所

个人简介

任丽丽,1974年生,病原生物学研究所研究员,博士生导师。1993年考入白求恩医科大学(现吉林大学)临床医学专业,1998年获得学士学位。1999年在吉林大学基础医学院病理学与病理生理学专业攻读硕士学位。2002年在原中国预防医学科学院(现中国疾病预防控制中心病毒病预防控制所)免疫学专业攻读博士学位,从事重要病毒形态发生及其致病机制研究。2010年获聘副研究员,2016年获聘研究员,牵头承担国家自然科学基金和科技重大专项项目。


主要研究方向

重症呼吸道感染病原学与重要呼吸道病毒的致病机制。从呼吸道微生物组角度解析重症感染的病原学特征,基于病毒感染后机体的损伤修复特征阐释重症感染机制。


代表性成果

全国十大赌博官网

图片

1. Ren L#, Wang Y#, Zhong J#, Li X, Xiao Y, Li J, Yang J, Fan G, Guo L, Shen Z, Kang L, Shi L, Li Q, Li J, Di L, Li H, Wang C, Wang Y, Wang X, Zou X, Rao J, Zhang L, Wang J, Huang Y, Cao B*, Wang J*, Li M*. Dynamics of the Upper Respiratory Tract Microbiota and its Association with Mortality in COVID-19. Am J Respir Crit Care Med. 2021, 204(12):1379-1390. (IF= 21.405)

2. He Z#, Ren L#, Yang J#, Guo L#, Feng L#, Ma C, Wang X, Leng Z, Tong X, Zhou W, Wang G, Zhang T, Guo Y, Wu C, Wang Q, Liu M, Wang C, Jia M, Hu X, Wang Y, Zhang X, Hu R, Zhong J, Yang J, Dai J, Chen L, Zhou X, Wang J*, Yang W*, Wang C*. Seroprevalence and humoral immune durability of anti-SARS-CoV-2 antibodies in Wuhan, China: a longitudinal, population-level, cross-sectional study. Lancet. 2021, 397(10279):1075-1084. (IF=79.321)

3. Ren L#, Fan G#, Wu W#, Guo L#, Wang Y#, Li X#, Wang C, Gu X, Li C, Wang Y, Wang G, Zhou F, Liu Z, Ge Q, Zhang Y, Li H, Zhang L, Xu J, Wang C, Wang J*, Cao B*. Antibody Responses and Clinical Outcomes in Adults Hospitalized with Severe Coronavirus Disease 2019 (COVID-19): A Post hoc Analysis of LOTUS China Trial. Clin Infect Dis. 2021, 72(10):e545-e551. (IF=9.079)

4. Han Z#, Rao J#, Xie Z#, Wang C, Xu B, Qian S, Wang Y, Zhu J, Yang B, Xu F, Lei X, Guo F, Zhao Z, Ren L*, Wang J*. Chemokine (C-X-C motif) Ligand 4 is a Restrictor of Respiratory Syncytial Virus Infection and an Indicator of Clinical Severity. Am J Respir Crit Care Med. 2020, 202(5):717-729. (IF=17.277, C100)

5. Huang C#, Wang Y#, Li X#, Ren L#, Zhao J#, Hu Y#, Zhang L, Fan G, Xu J, Gu X, Cheng Z, Yu T, Xia J, Wei Y, Wu W, Xie X, Yin W, Li H, Liu M, Xiao Y, Gao H, Guo L, Xie J, Wang G, Jiang R, Gao Z, Jin Q, Wang J*, Cao B*. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020, 395(10223):497-506. (IF=79.321, F1000, C100)

6. Ren LL#, Wang YM#, Wu ZQ#, Xiang ZC#, Guo L#, Xu T#, Jiang YZ, Xiong Y, Li YJ, Li XW, Li H, Fan GH, Gu XY, Xiao Y, Gao H, Xu JY, Yang F, Wang XM, Wu C, Chen L, Liu YW, Liu B, Yang J, Wang XR, Dong J, Li L, Huang CL, Zhao JP, Hu Y, Cheng ZS, Liu LL, Qian ZH, Qin C*, Jin Q*, Cao B*, Wang JW*. Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study. Version 2. Chin Med J (Engl). 2020, 133(9):1015-1024. (IF=1.196, C100, R)

7. Shen Z#, Xiao Y#, Kang L#, Ma W#, Shi L, Zhang L, Zhou Z, Yang J, Zhong J, Yang D, Guo L, Zhang G, Li H, Xu Y, Chen M, Gao Z, Wang J, Ren L*, Li M*. Genomic diversity of SARS-CoV-2 in Coronavirus Disease 2019 patients. Clin Infect Dis. 2020, 71(15):713-720. (IF=8.313, F1000, C100)

8. Yu J#, Liu C#, Xiao Y#, Xiang Z, Zhou H, Chen L, Shen K, Xie Z*, Ren L*, Wang J*.  Respiratory syncytial virus seasonality, Beijing, China, 2007–2015. Emerg Infect Dis. 2019, 25(6):1127-1135. (IF=7.185)

9. Yan F#, Xiao Y#, Li M, Zhang H, Zhang R, Zhou H, Shen H, Wang J, Li W*, Ren L*. Metagenomic Analysis Identified Human Rhinovirus B91 Infection in an Adult Suffered Severe Pneumonia. Am J Respir Crit Care Med, 2017, 195(11): 1535-1536. (IF=15.087)

10. Ren L#, Gonzalez R#, Wang Z#, Xiang Z#, Wang Y#, Zhou H, Li J, Xiao Y, Yang Q, Zhang J, Chen L, Wang W, Li Y, Li T, Meng X, Zhang Y, Vernet G, Paranhos-Baccalà G, Chen J, Jin Q*, Wang J*. Prevalence of human respiratory viruses in adults with acute respiratory tract infections in Beijing, 2005-2007. Clin Microbiol Infect, 2009, 15(12): 1146-1153. (IF=5.2)